Local anesthetics like lidocaine temporarily stop pain signals by blocking the flow of which ions into nerve cells?
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Lidocaine and similar local anesthetics work by binding to and blocking sodium channels in nerve membranes. This prevents the rapid influx of sodium ions required to generate and conduct electrical pain signals to the brain. Interestingly, local anesthetics are chemically related to cocaine, which was the first local anesthetic ever discovered.
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Source: Wikipedia (CC BY-SA)
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